Graves' disease is an autoimmune disorder that affects the thyroid gland, causing it to produce too much thyroid hormone. This condition, also known as hyperthyroidism, can lead to a wide range of symptoms including weight loss, rapid heartbeat, tremors, and anxiety. In severe cases, it can cause life-threatening complications such as heart failure and psychosis.
The exact cause of Graves' disease is unknown, but it is believed to be the result of a combination of genetic and environmental factors. It is more common in women and tends to occur in people who have a family history of autoimmune disorders.
Diagnosis of Graves' disease typically involves a physical exam, blood tests to measure thyroid hormone levels, and imaging tests such as ultrasound or nuclear medicine scans. Treatment options include medications to control hormone levels, radioactive iodine therapy to destroy thyroid tissue, or surgery to remove the thyroid gland.
Research on Graves' disease has focused on identifying the genetic and environmental factors that contribute to its development and finding new and more effective treatments. One area of study has been the role of autoantibodies in the development of the disease. Autoantibodies are proteins produced by the immune system that mistakenly attack the body's own tissues. In Graves' disease, autoantibodies stimulate the thyroid gland to produce too much hormone.
Another area of research has been the use of immunosuppressive drugs to treat Graves' disease. These drugs work by suppressing the immune system, which may help to reduce the production of autoantibodies and slow the progression of the disease. However, these drugs can also have serious side effects, including an increased risk of infections and cancer.
More recently, researchers have been investigating the use of biologics, which are proteins made by living cells that can specifically target and neutralize certain immune cells or molecules. Biologics may be a safer and more effective alternative to immunosuppressive drugs for the treatment of Graves' disease.
Overall, while much progress has been made in understanding and treating Graves' disease, there is still much research to be done to identify the underlying causes of the disease and develop new and more effective treatments.
Graves Disease Research Paper
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Research Paper On Graves Disease
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Andrew Wakefield, a British gastroenterologist of London's Royal Free Hospital published a paper in the journal the Lancet in which he stated the results of a study that he did. The …show more content… When it goes untreated, there are physical signs and symptoms that may develop such as an enlarged thyroid gland, mild to severe eye problems, and even skin lesions with a thickening of the skin of the tibia. However, no one knows what exactly caused this disease; it causes the thyroid gland to produce too much thyroid hormone hyperthyroidism. In which your immune system then creates an antibody that causes the thyroid to grow and make more thyroid hormone than your body needs. Marcus Martinez during a routine physical, made me aware, that I more than likely have Graves Disease. On average there are over 3. Thyroid hormone production is.
