Thalassemia essay. Thalassemia Essay Example 2022-11-07

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A literature review is a critical analysis of the existing research on a particular topic. It is an essential part of any research project as it helps to contextualize the research and situate it within the larger body of knowledge on the topic. Writing a literature review can be a challenging task, especially for those who are new to the process. However, with some careful planning and organization, it is possible to write a comprehensive and well-written literature review. Here are some tips to help you get started:

  1. Define your research question or topic: The first step in writing a literature review is to define the research question or topic that you are interested in. This will help you to focus your review and ensure that you are only including relevant literature.

  2. Search for relevant literature: Once you have defined your research question or topic, the next step is to search for relevant literature. This can be done through a variety of sources, such as databases, libraries, and online sources. Make sure to search for both primary and secondary sources, as well as both published and unpublished materials.

  3. Read and evaluate the literature: As you begin to read and evaluate the literature, it is important to take good notes and keep track of your sources. This will help you to remember important details and make it easier to write your review. As you read, consider the following questions:

  1. Organize the literature: Once you have read and evaluated the literature, it is important to organize it in a logical and coherent manner. One common way to organize a literature review is to group the studies by theme or topic. Alternatively, you can organize the literature chronologically or by research method.

  2. Write the review: Once you have organized the literature, it is time to begin writing your review. Start by introducing the research question or topic and providing some background information. Next, summarize the main findings and arguments of the studies you have reviewed. Finally, conclude your review by discussing the implications of the literature and any future directions for research.

In summary, writing a literature review requires careful planning and organization. By defining your research question, searching for relevant literature, reading and evaluating the literature, and organizing and writing your review, you can produce a comprehensive and well-written review that adds to the existing body of knowledge on your topic.

Thalassemia is a group of inherited blood disorders that affect the body's ability to produce hemoglobin, a protein found in red blood cells that carries oxygen to the body's tissues. Hemoglobin is made up of two types of protein chains, alpha and beta. Thalassemia occurs when there is a deficiency or absence of one or both of these protein chains, resulting in anemia and other complications.

There are two main types of thalassemia: alpha thalassemia and beta thalassemia. Alpha thalassemia occurs when there is a deficiency or absence of the alpha protein chain, while beta thalassemia occurs when there is a deficiency or absence of the beta protein chain.

Alpha thalassemia is further divided into four subtypes, depending on the severity of the deficiency. The most severe form is alpha thalassemia major, which is also known as hydrops fetalis or Hb Bart's. This form occurs when all four alpha genes are absent or mutated, and it is usually fatal in utero or shortly after birth. The milder forms of alpha thalassemia are alpha thalassemia trait, alpha thalassemia intermedia, and alpha thalassemia minor. These forms can cause mild to moderate anemia, but do not typically cause serious complications.

Beta thalassemia is also divided into two subtypes: beta thalassemia major (also known as Cooley's anemia) and beta thalassemia minor. Beta thalassemia major is the most severe form and is characterized by a severe deficiency of beta protein chain production, leading to severe anemia and other complications. Beta thalassemia minor is a milder form of the disease that may not cause any symptoms or may only cause mild anemia.

Thalassemia is caused by mutations in the HBB gene, which provides instructions for making the beta protein chain of hemoglobin. These mutations can be inherited from one or both parents. Thalassemia is most common in people of Mediterranean, African, and Southeast Asian ancestry, but it can occur in people of any ethnicity.

The main symptoms of thalassemia are anemia, fatigue, and an enlarged spleen. Anemia is caused by a deficiency of red blood cells or hemoglobin, which leads to a lack of oxygen in the body's tissues. This can cause fatigue, shortness of breath, and pale skin. An enlarged spleen is a common complication of thalassemia and occurs when the spleen tries to compensate for the lack of red blood cells by overproducing them. This can lead to an enlarged spleen and a decrease in the number of other blood cells, such as white blood cells and platelets.

Diagnosis of thalassemia is typically made through a combination of a physical exam, medical history, and laboratory tests. A complete blood count (CBC) can be used to measure the levels of red blood cells, hemoglobin, and other blood cells. Hemoglobin electrophoresis can be used to determine the type of thalassemia and the severity of the deficiency. Genetic testing can also be used to confirm a diagnosis and determine the specific mutation causing the disease.

Treatment of thalassemia depends on the severity of the disease and may include blood transfusions, iron chelation therapy, and bone marrow transplantation. Blood transfusions can be used to increase the number of red blood cells and hemoglobin in the body. Iron chelation therapy is used to remove excess iron from the body, which can accumulate as a result of frequent blood transfusions. Bone marrow transplantation is a more aggressive treatment option that involves replacing the bone marrow with

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thalassemia essay

These include loss of appetite, slowdevelopmentorgrowth, puberty delays, fatigue, shortness of breath, pale skin, dark urine due to degeneration of rd blood cells, jaundice, bone complications in the face, and enlargement of the liver, spleen or heart NHLBI, 2012. More signs of Thalassemia can be an enlarged spleen. In healthy people, hemoglobin carries oxygen to tissues and cells throughout the body. Clinical Alpha Thalassemia Essay I. . . It also carries two chains called alpha globin chains and beta globin chains.

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Free Thalassemia Essays and Papers

thalassemia essay

. . Professional guide to diseases 10th ed. Some of the Fugates children had just that and they had the disease while some were just carriers of the disease. This disease cause a person to feel weak and have slower growth. The dangers of iron overload: Bring in the iron police Myers, T. .

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Research Paper On Thalassemia

thalassemia essay

HbHdisease and Hb Bart syndrome hemoglobin Bart hydrops fetalis syndrome or alpha thalassemia major. This is aninherited disorder that reduces the production of hemoglobin, aniron-rich protein thatis foundin thered blood cells and are responsible for the transportation of oxygen to cells throughout the body. Excess amount of bilirubin can be toxic, but low amount of unconjugated hyperbilirubinemia might protect against cardiovascular diseases and tumor development. Beta Thalassemia is prominent in people from the Mediterranean region, Italy, Middle East, Greece, Southeast Asia, Africa, and Southern China. The cure is very costly and requires long-term management. To develop thalassemia major one must have inherited the gene from both majors. Sickle cell disease is caused by a mutation in the hemoglobin gene.

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Thalassemia Essays

thalassemia essay

The present paper focuses on the phenomenon of thalassemia, its pathophysiology, diagnostic testing and its peculiarities as well as treatment modalities and other relevant practical aspects. . For this paper the focus will be on beta thalassemia. It is always good to take out extra information from pedigree charts and genetic testing as it can improve the accuracy of risk assessment drastically. Red blood cells carry hemoglobin which carries oxygen through the entire body. Proper identification and treatment of this anemia is important as it has a direct effect in the longevity of the patient. Approximately 9000 thalassemic children are born in India every year.

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Free Essay: Thalassemia

thalassemia essay

Prenatal diagnostic centres should be established both in rural and urban areas. This disorder is inherited from two parents with abnormal genes that are heterozygous Rr. Endothelial dysfunction and oxidant status in pediatric patients with hemoglobin E-b thalassemia. VIP support VIP support ensures that your enquiries will be answered immediately by our Support Team. Beta Thalassemia Beta thalassemia is an inherited blood disorder characterized by the abnormal production of a blood protein called hemoglobin. Bilirubin can help in diagnosing liver and blood disorder, the complex metabolism plays an important role in drug metabolism.

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Thalassemia Essay Sample

thalassemia essay

It occurs when the body makes less Thalassemia is a blood disorder transferred through families. Thalassemia Thalassemia was discovered by pediatric hematologist Thomas Cooley June 23, 1871 - October 13, 1945 Clark, 2010. When red blood cells can't perform tasks and work, they die and your body doesn't function correctly, leading to serious consequences. . Treatments for Thalassemia include Blood Transfusions, Iron Chelation Therapy, Folic Acid Supplements, Blood and Marrow Stem Cell Transplant, as well as treatments that researchers are still conducting experiments on.

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Thalassemia Essay

thalassemia essay

. The Detroit physician investigated the similarities in the characteristics and presentation of children with anemia of Greek and Italian descent. The 31-year-old unmarried Vikram worked twice as hard in his job to make up for the time he took off for medical reasons. This entails doing blood tests on family members as well as evaluating the family history. Are you a carrier of Beta Thalassemia Beta thalassemia is placed under the group of inherited blood disorders that can be transferred from both the genes of parents into their children. This affects transferrin levels in the blood in ACD because transferrin is a negative acute phase reactant. Beta thalassemia is divided into three subcategories.

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Thalassemia

thalassemia essay

Mild anemiais exhibitedbypeoplehaving alpha or beta thalassemia trait, though some may not show symptoms apart from feeling fatigued Giardinaet al, 2008. When given a blood transfusion, the patient receives new healthy red blood cells and more hemoglobin through a needle being inserted into their vein. Alpha thalassemia usually results from deletions of two genesnamelyHBA1 and HBA2. Thalassemia is a disorder that affects the blood of those affected with the disease. Who is at risk? Hereditary counselling is essentially the most central angle that can help patients in different ways it not just covers the zones of fitting and right determination additionally administration and steady treatment. The given test will outline the main directions of treatment and family counseling that is an essential element of the holistic therapy in case of thalassemia diagnosis. .


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Thalassemia Essay Example

thalassemia essay

. The writers of supremewritingservice. If one or two of these genetic factors or materials are deficient, it will form into the beta thalassemia disease. First, it is crucial to note that both children and adults experience pain. Also, there is no genetic editing done in past that has successfully correct a homozygous point mutation in human embryo. Thalassemia is an inherited disorder.

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